The advert, titled "Dream Crazy", has Kaepernick narrating over images and footage of various athletes with inspirational stories, including National Basketball Association icon LeBron James, tennis star Serena Williams and Kenyan runner Eliud Kipchoge.
And now, the first video ad featuring Colin Kaepernick just rolled out.
Kaepernick became well-known for his take a knee protest during National Football League games in 2016, in support of the Black Lives Matter movement and to protest police brutality in the US.
Kaepernick implores "Don't become the best basketball player on the planet, be bigger than basketball, ' with a clip of NBA star Lebron James opening his 'I Promise" school.
Nike will feature Kaepernick on several platforms, including billboards, television commercials and online ads. As the post and the story went viral a large a mount of people starting burning their Nike's and taking a stance against the company.
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"Nike is getting absolutely killed with anger and boycotts", Mr Trump tweeted after the sportswear giant chose to feature Kaepernick in a new campaign. I would love to see how they would protest Home Depot: 'The walls in my house must go!' And also, I'm not going to lie, those flaming Nikes makes me nearly want to pay more.
In the ad - which will make its television debut during the Thursday night matchup between the Philadelphia Eagles and Atlanta Falcons - Kaepernick performs the voiceover before later being revealed as the narrator.
"What non-believers fail to understand is that calling a dream insane is not an insult-it's a compliment", Kaepernick says in the spot. People threatened a boycott on social media, and the company's stock fell nearly 3%.
"We also believe that those who know what sacrifice is all about are more likely to be wearing a military uniform than an athletic uniform", Davis said.
Carlson then asked Portnoy how Nike is helping the cause of civil rights if it's trying to sell expensive shoes to people who can't afford them.