The most well-known example of the consequences of a pyroclastic flow can be found in Italy where the two Roman towns of Pompeii and Herculaneum were covered under a thick blanket of ash in 79 AD. "There are injured, burned and dead people", Sergio Cabañas, the general secretary of Guatemala's CONRED national disaster management agency, said on radio.
The disaster agency said 3265 people had been evacuated.
Temporary shelters have been set up for about 3,000 residents who have been evacuated.
Search and rescue operations for the missing and dead have been suspended due to low light and risky conditions, and will resume early on Monday morning, he said.
One village was extremely affected by running lava causing deaths and injuries.
Her husband, Joel Gonzalez, said his father had also been unable to escape and was believed to be "buried back there, at the house".
Volcan de Fuego, situated on the borders of Chimaltenango, Escuintla and Sacatepéquez, sent out an 8km stream of lava, with smoke and ash surrounding the area.
Guatemala's Fuego volcano claims lives in deadly eruption today
Guatemalan President Jimmy Morales said on Facebook that the national emergency system had already been activated.
The eruption forced the Guatemala City's La Aurora global airport to shut down its only runway due to the presence of volcanic ash and to guarantee passenger and aircraft safety, Guatemala's civil aviation authority said in a Tweet.
Guatemala's Volcan de Fuego is seen erupting, June 3, 2018.
"We saw the lava was pouring through the corn fields and we ran towards a hill", Consuelo Hernandez, a survivor, told Al Jazeera. Pyroclastic flows (a mixture of gas, hot rock and volcanic matter) from the eruption quickly engulfed nearby communities El Rodeo and La Reunion.
Volcan de Fuego, Spanish for "volcano of fire", exploded shortly after noon on Sunday. All came from the hamlets of Los Lotes and El Rodeo, but only 13 had been identified so far because the flows that reached temperatures as high as 1,300 degrees Fahrenheit (700 Celsius) had so disfigured the bodies.
The eruption officially ended late Sunday, according to the Guatemala's National Institute of Seismology, Vulcanology, Meteorology and Hydrology.
Officials have advised people to wear masks as protection against falling ash.
Disaster agency spokesman David de Leon says about 300 people have been evacuated from nearby villages, which are being blanketed by ash as fiery smoke billows almost four miles into the sky.
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