Of 187 people with information available, 89 (48 percent) have been hospitalized, including 26 people who developed hemolytic uremic syndrome, a type of kidney failure.
According to the CDC, 25 more ill people from 13 states were added to the lettuce investigation since the last update on May 16. That means it is unlikely that any romaine lettuce from the Yuma growing region is still available in people's homes, grocery stores or restaurants due to its 21-day shelf life.
Two of the victims were from Minnesota, with the other three from Arkansas, California and NY. Health officials said there are now 197 cases across 35 states. On Friday, health officials said they have learned of four more - another in California as well as one each in Arkansas, Minnesota and NY.
The first illnesses occurred in March, and the most recent began on May 12, according to the Centers for Disease Control and Prevention.
Officials urge anyone who thinks they may be ill with an E. coli infection to see their doctor.
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Earlier this month, President Trump complained on Twitter about the money being spent on the "witch hunt". Trump's former campaign manager, Paul Manafort, is among 19 individuals and entities indicted by Mueller.
"Some people who became sick did not report eating romaine lettuce, but had close contact with someone else who got sick from eating romaine lettuce".
They haven't been able yet to trace the affected lettuce back to one particular farm, processor or distributor, FDA authorities said in an update Thursday.
The growing season in the Yuma, Ariz., region, which produced the contaminated lettuce, ended April 16. Gottlieb is Commissioner of the U.S. Food and Drug Administration, and Ostroff is FDA's Deputy Commissioner for Foods and Veterinary Medicine.
Some of the tainted lettuce tied to the massive E. coli outbreak in the United States was from Imperial County.
Symptoms of E. coli vary, but include may include stomach cramps, fevers, bloody diarrhea and vomiting among others.