Teenagers Phil Foden and Brahim Diaz were sent on in the closing stages for their fifth league appearances of the season, ensuring they will both receive a title winners' medal.
Guardiola leapt out of his seat in the dugout to punch the air while Jesus whipped off his shirt in celebration in front of City's delirious fans. "You can not achieve 100 points if you drop games and think it doesn't matter", he said.
The Blues won it at a frightening level, breaking numerous Premier League records while positioning themselves into discussions about being the greatest Premier League team of all time, alongside the likes of Sir Alex Ferguson's Red Devils of 1999 and Arsene Wenger's Invincibles team of 2004.
"All season we didn't surrender, we never gave up and tried until the end".
"Our rhythm was not so high but during the game we were focused and at the end the excellent pass from Kevin and incredible finish from Gabriel made the difference to achieve that".
City manager Guardiola insists the pursuit of a host of records has enabled his Premier League title winners to "keep focus" over the last weeks.
They have also scored the most goals in a single Premier League campaign (106), won the most games (32) and amassed the most consecutive victories (18) in a season that has seen them ranked along with the best teams in the history of English football.
"Numbers are numbers, they are the outcome of the way we played".
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"I want to win everything we can, all of the competitions", he continued.
"We were better than our opponents and the records we broke came from the way we played".
At the wrong end, West Brom finished bottom and Stoke beat Swansea, as all three sides ended up in the Championship.
But they had no intention of letting the impending party distract them on the south-coast.
City began to show a little more of their usual attacking fluidity in the second half but chances remained at a premium for Guardiola's side, Raheem Sterling hitting the post and John Stones seeing his header tipped over the crossbar.
So when there is a fight for the Premier League that goes into the final day or a relegation battle, it could bring for a very dramatic conclusion.
Extending that form out over the course of 38 games is now the challenge for the German to deliver a first league title since 1990.