McCabe, 49, served in government for 22 years, but had become a frequent target for President Trump, who has politicized attacks on the nation's intelligence services since taking office.
The fact that McCabe did not vote for him.
"I want to believe the path you threw out for consideration in Andy's office - that there's no way he gets elected - but I'm afraid we can't take that risk", Strzok wrote in a message to page on August 15, 2016. "America needs you", Comey tweeted.
An FBI inspector general is now investigating the handling of the Clinton case.
He questioned how Mr McCabe could be in charge of the investigation into Mrs Clinton when his wife had received donations from "Clinton puppets".
White House counsel was 'fed up' with Trump
"I don't think there's a need for legislation right now to protect Mueller ", he said. Mueller is the best person to look at it, not me opine about something I don't know.
Angered by that investigation, Trump fired Comey on May 9.
FBI Deputy Director Andrew McCabe has left the building - and no doubt there was some cheering in the Oval Office about the earlier-than-expected departure.
The news comes after months of conflict-of-interest complaints from Republicans over McCabe's ties to the Democratic Party, including his wife receiving donations for a failed 2015 Senate run from a group tied to former Virginia Gov. Terry McAuliffe. Trump dismissed the report as "Fake News".
Mrs Clinton was cleared of criminal wrongdoing in her misuse of a personal email server while serving as secretary of state.
Federal Bureau of Investigation deputy director Andrew McCabe stepped down from his role following several weeks of harsh criticism targeted at the US President. He regarded McCabe as a "dedicated public servant".
"How can FBI Deputy Director Andrew McCabe, the man in charge, along with leakin' James Comey, of the Phone Hillary Clinton investigation (including her 33,000 illegally deleted emails) be given $700,000 for wife's campaign by Clinton Puppets during investigation?" the president tweeted on December 23. 90 days to go?!' wrote Trump.
He is said to have been part of ongoing tensions between the FBI and White House over an ongoing investigation into alleged collusion between Trump's election campaign and Russian Federation.