The second leg is being played in the hallowed grounds of the Stadio San Siro, though, and Gli Azzurri will be hoping that will be the advantage they need to overcome their deficit.
As such, anything other than qualification is nearly certain to result in the sacking of current coach Giampiero Ventura with a number of names being linked to the Azzurri bench.
Gian Piero Ventura's men will be the first Azzurri team to fail to qualify for the World Cup since 1958 if they are unable to overturn Jakob Johansson's deflected strike.
The Livorno native recently agreed an extension to keep him at the club until 2020, however he has previously reported being interested in coaching the national side, should the opportunity present itself.
Ventura has come under fire for stubbornly sticking to a failing tactical system. I don't want to think it's the game of life but I'm convinced that, with the help of the fans, we will do it.
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Senator John McCain (R-AZ) the 2017 Liberty Medal at the Independence Hall in Philadelphia, Pennsylvania, U.S., October 16, 2017. Biden said he doesn't know whether he would have been able to beat Trump in last year's election.
Buffon, who like Andrea Barzagli and Daniele De Rossi is a veteran of the 2006 World Cup-winning campaign, admitted the team were under pressure with national pride at stake.
"Losing forbidden", wrote Turin mayor Chiara Appendino on Twitter with a joke in reference to Ikea, the most famous Swedish brand in the world: "They are famous for making homes welcoming, it would be a shame not to send them home".
Before the 3-0 defeat in Madrid, Italy was unbeaten in 50 World Cup or Euro qualifying games. I'd like to return in the World of football, but I'd only return to Italy or AC Milan.
This time around, Italy can not afford such imbalances and poor decisions - they have no more margin for error, especially if their defense allows Sweden to score a tiebreaking away goal.
"They developed well and have good individual players. We have nothing to lose and we will go onto the pitch to give a great performance".